Following this checklist will ensure your email messages successfully reach your recipients and will increase the likelihood of your messages being accepted, not marked as spam/junk, by your recipients.

Things for you to do:

Send your initial lists to clean lists (people you know well who won't hit the spam button)
Use lead nurturing to send relevant content based on roles, actions and interests
Only send to old database contacts once you develop a good reputation
Consider using a different but related domain for sending emails
Setup SenderID and SPF
Setup postmaster@ and abuse@ email addresses
Avoid buying, renting or borrowing lists from 3^rd parties
Check the integrity of your contact lists before and after an upload
Create great marketing content
Segment your marketing content into smaller chunks vs. sending "clusters"
Get people's permission before adding them to an email marketing track
Embed a "Safely Unsubscribe" and "Privacy Policy" link at the bottom of your messages
Do not be too aggressive with your email communications especially at first (think dating)
Use auto-responders that cross promote
Use an active email address as your reply-to email address
Make the unsubscribe process easier than the subscribe process
Use your colors and logo in your content so your recipients recognize you
Don't include too many images (<=4) in your messages
Keep your messages small (< 37K Bytes)
Follow CAN-SPAM Act requirements

Things to do with Lead Liaison's support:

Setup DKIM/DomainKeys
Send from a dedicated IP address, not a shared IP address
Start by warming up your IP address and sending a small amount (<1,000) of messages
Process hard and soft bounce emails and test
Check blacklist records occasionally to make sure your dedicated IP address is not on any lists
Make sure you tag your contacts with a lead source
Segment current and future contacts by building Lead Liaison Segmentations
Build several landing pages and web forms to increase lead capture and build subscribers
Keep web form fields simple
Send a text representation with your html email
Monitor feedback loops and resolve spam complaints
Avoid using spam-like words ("free") in your messages